Anti-ALDH2 Monoclonal Antibody
品牌：solarbio | 货号：K000109M


 

 


    

        

            
商品货号：
            
商品品牌：
            
规格
            
基本售价：
            
选择规格
        
    
    

        

            
K000109M-50ul
            
solarbio
            
50ul
            
960.00元
            

        
        

            
K000109M-100ul
            
solarbio
            
100ul
            
1600.00元
            


            

            
        
    

 





    

        

            
英文名称
            
Anti-ALDH2 Monoclonal Antibody
        
        

            
别名
            
ALDH-E2;ALDHI;ALDM
        
        

            
应用
            
WB
        
        

            
稀释比例
            
WB 1:1000.
        
        

            
交叉反应
            
Human Mouse Rat Monkey Hamster
        
        

            
蛋白分子量
            
56kDa
        
        

            
Gene ID
            
217
        
        

            
保存
            
Store at -20°C. Avoid freeze / thaw cycles.
        
        

            
储存液
            
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
        
        

            
纯化方法
            
Affinity purification
        
        

            
亚型
            
IgG1
        
        

            
免疫原
            
Purified recombinant human ALDH2 protein fragments expressed in E.coli
        
        

            
性状
            
液体
        
        

            
Public Immunogen Range
            
Purified recombinant human ALDH2 protein fragments expressed in E.coli
        
        

            
Subcellular Locations
            
Mitochondrion matrix
        
        

            
Swiss Prot
            
P05091
        
        

            
克隆号
            
8D4-D6-D11
        
        

            
克隆类型
            
Monoclonal Antibody
        
        

            
背景资料
            
This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase,cytosolic and mitochondrial,can be distinguished by their electrophoretic mobilities,kinetic properties,and subcellular localizations.Most Caucasians have two major isozymes,while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform,which has a low Km for acetaldehydes,and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq,Mar 2011]